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Criteria Inclusion Criteria: A subject must sex sites reviewed all of the following criteria to be eligible to participate in this study: Provides written informed consent prior to initiation of any study procedures. Be able to understand and agrees to comply with planned study procedures and be available for all study visits. Agrees to the collection of venous blood per protocol. Periodic abstinence [e. Must use at least one acceptable primary form of contraception for at least 30 days prior to the first vaccination and at least one acceptable primary form of contraception for 60 days after the last vaccination.
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Has a history of alcohol abuse or other recreational drug excluding cannabis use within 6 months before the sex sites reviewed vaccine administration. Neurological or neurodevelopmental conditions e. Has a positive test result for hepatitis B surface antigen, hepatitis C virus antibody, or human immunodeficiency virus HIV types 1 or 2 antibodies at screening. Has ly participated in an investigational study involving lipid nanoparticles LNPs a component of the investigational vaccine assessed in this trial.
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A course of treatment usually lasts for at least 6 months, although longer courses are sometimes recommended and some people with recurrent problems may be advised to take them indefinitely. The use of low dose topical, ophthalmic, inhaled and intranasal steroid preparations will be permitted.
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